Echo Train Length

Echo train length (ETL), also known as turbo factor, determines the number of additional refocused echoes to be acquired in a spin echo based sequence and is used to decrease scan time. Depending on the sequence, this number can be selected by the user (as in FSE) or is controlled indirectly (as in HASTE) through other parameters such as phase encoding steps. When selecting an echo train length, it is important to remember that the refocused echo is created from an additional refocusing RF pulse. As will be discussed further down, this can have implications for controlling SAR and TR. This page will primarily focus on echo train length as used in the fast spin echo. See HASTE or 3D FSE pages for more explanation of ETL in those sequences.

Consider 1 slice of a T2 weighted spin echo sequence with a phase encoding matrix of 256; to fully acquire the image 256 lines of k-space are needed, and will be acquired 1 line at a time. For an example, if the TR is 3000ms, this will need to be repeated 256 times: 3000msx256 = 768,000ms or ~12.8 minutes. This is quite inefficient, as only 1 echo is acquired with each TR, and the rest of the TR is just spent waiting. To reduce imaging time, let's acquire 16 echoes within that 3000ms TR, the math now looks like this: (3000msx256)/16 = 48,000ms or ~48 seconds. Much faster!

When using a fast spin echo, the TE parameter behaves differently than in the traditional spin echo. The selected TE is now one of multiple echoes, and is placed at the center of k-space which allows it to dominate the image contrast; this is known as the 'Effective' TE. Unlike a traditional spin echo where there is only 'waiting time' before or after the TE, the fast spin echo will always start with the shortest TE and extend out to the end of the selected ETL. For example, in a fast spin echo where the shortest echo is 10ms and there is a 10ms space between each echo, an ETL of 10 will result in echoes at 10ms, 20ms, 30ms, 40ms, etc until 100ms. Any of those echoes can be selected as the effective TE and placed at the center of k-space. There a few important things to take away from this behavior:

1. There are multiple echoes at varying TE values that will be acquired during a fast spin echo, always
2. The effective TE is the primary echo contributing to image contrast, but not the only echo that can influence it
3. Only the minimum, maximum, and echoes between those end points can be chosen as the effective TE

When selecting the ETL, it is important to consider the contributions of all the echoes within the ETL to image quality, as there are some special behaviors that occur with trains of RF pulses and echoes. Very long ETL's will result in echoes that may extend out far beyond the desired effective TE. The further out the echo, the more T2 decay will occur and the 'quality' of the echo will degrade and contribute to image blurring. Additionally, a long ETL means that many more refocusing pulses will be required; this will increase SAR and also lead to some degree of tissue saturation and magnetization transfer effects. Long ETL's also take up significantly more space within the TR, so there will be a tipping point where increasing ETL will no long decrease imaging time, as the TR will have to be increased to make room for all the additional echoes. Below is an example of a T2 fast spin echo with different ETLs: 13, 24, 32, 64. Notice how edge details rapidly become blurred as the ETL is increased, and the blurring is preferentially in the phase encoding direction. Keep an eye on the maximum TE when selecting the ETL, it will increase rapidly as ETL is increased.

Guidelines

• T1 Contrast: ETL 2-4, Maximum TE ~30ms
• PD Contrast: ETL 7-11, Maximum TE ~100ms
• T2 Contrast: ETL 16-24, Maximum TE ~250ms

So, which echo is the best echo in the echo train? Generally speaking, it is good to select an effective TE near the midpoint of the echo train, as not all echoes are created equally. Very early echoes do tend to demonstrate some degree of blurring, and greater flow artifacts. TE's around the mid point of have achieved some degree of steady state signal, have both stimulated and refocused echo signals, and tend to have sharper edge details. Very late TE's in the ETL may suffer from too much signal loss due to T2 decay. This behavior can even be seen in relatively short ETL's! The gif below is a T1 FSE with 4 echoes, 8ms apart, therefore TE's at 8ms, 16ms, 24ms, and 32ms. All parameters are constant other than the effective TE. Note how the flow artifact from the vessels decreases as the effective TE is longer, and how the edge details become more crisp. the second gif on the right is a T2 FSE with min/max TE's at 10ms and 180ms. Although it is a broccoli, the edge detail changes are still demonstrative of this behavior.

Broadly, image quality will be acceptable across a pretty wide range of Effective TE and ETL combinations as long as no single parameter is pushed to the extreme. In this grey area, there is nuance, trial and error, and even individual scanner behavior. In the example below, different combinations of TE and ETL are chosen, all within the normal acceptable ranges of 2-4 ETL and an effective TE under 30, notice how much variability there is even within the recommended ranges!